SNHG12 and colorectal carcinoma: We verified the up-regulated expression patterns of SNHG12 in CRC tissues and cell lines, and further examined the association with the clinical-pathological characteristics of patients with CRC (Fig. 4d, e, Table 1), proving that SNHG12 is positively involved in CRC invasion and distal metastasis by having an oncogenic role in CRC.