The expression alteration of four genes that were previously described in other studies related to several neurological disorders were detected in this study, namely VCAM1, TRPM4, GDF10 and NTN1. The first three were detected as significantly upregulated in the Adj-injected sheep, while the latter was found to be upregulated in Adj vs Control and Adj vs. Vac comparisons. The gene discussed is VCAM1; the disease is nervous system disorder.