GDPD3 and chronic myelogenous leukemia, BCR-ABL1 positive: Lyso-PAF (platelet-activating factor) was higher in Gdpd3+/+ tet-CML BM cells than in normal WT BMMNCs, but decreased in Gdpd3−/− tet-CML BM cells compared to Gdpd3+/+ tet-CML BM cells (Fig. 4c).