GDPD3 and chronic myelogenous leukemia, BCR-ABL1 positive: Given that the Gdpd3 gene encodes a lysophospholipase D enzyme that hydrolyses lysophospholipids into LPAs8,9, we investigated levels of various LPAs predicted to be products of Gdpd3 activity in BM cells of normal WT, Gdpd3+/+ tet-CML and Gdpd3−/− tet-CML-affected mice.