GDPD3 and chronic myelogenous leukemia, BCR-ABL1 positive: We next performed a sophisticated global lipidomics analysis of 196 lipid mediators and discovered that several non-LPA lipid mediators were also markedly decreased in Gdpd3−/− tet-CML BM cells compared to Gdpd3+/+ tet-CML BM cells (Fig. 4).