TGFB1 and cancer: One of the hallmarks of fibroblasts is their ability to respond to TGFβ1 and become activated, resulting in enhanced properties of proliferation, migration and production of growth factors and extracellular matrix (ECM) which is the biology and function of fibroblasts in cancer In order to investigate the suppressive effect of CUDC-907 on myofibroblasts migration capacity, in vitro scratched assay and migration assay were employed.