Likewise, case fatality rate (CFR) of diabetes, CCVD and hypertension among patients with COVID-19 was 7.3%, 10.5%, and 6% respectively as per a meta-analysis of six published studies from China.24 25 This relative surge in CFR in comparison to other comorbidities emphasises the role of ACE receptor abundance in cardiovascular disorder and ACE-mediated damage by SARS-Cov-2, in the pathophysiology of patients with severe COVID-19. The gene discussed is ACE; the disease is Hypertension.