In these phenotypes, the possible presence of high-confidence resistance-associated mutations was searched in extended regions (full coding sequence and promoter regions) of genes from which only (most) critical regions are covered by Deeplex Myc-TB, as well in 14 other, secondary resistance-associated gene targets, outside the Deeplex Myc-TB target regions, such as the embA promoter region (including, e.g. the C-12T and C-16T mutations) or the extended ethA promoter region (including, e.g. the T-11C mutation) (supplementary table S9). This evidence concerns the gene SCN9A and tuberculosis.