Of the 2403 variants identified in the Deeplex Myc-TB targets by either method, 2373 (98.8%; 2293 SNPs and all 80 indels), including 797 (99.9%) resistance variants, were detected by both Deeplex Myc-TB and our WGS pipeline under low-frequency mode (validated for accurate SNP calling in accordance with recent guidelines [28]). Here, MYC is linked to tuberculosis.