MYC and tuberculosis: Likewise, most of the resistance predictions made only by direct Deeplex Myc-TB analysis on sputa from the Djibouti survey were due to resistance minority variants, undetected by MTBSeq/PhyResSE/Mykrobe in WGS data likely due to insufficient read depths and/or culture bias eliminating potentially less fit (resistant) subpopulations [37] before subjection to WGS.