IGF2BP2 and glioblastoma: Studies have shown that IGF2BP2 is upregulated in GBM tissues, promoting the proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) of GBM cells through the regulation of insulin-like growth factor 2 (IGF2) activity while further activating the phosphoinositide 3-kinases (PI3K)/AKT signalling pathway.