Among the genes with predictive value in adult low-grade gliomas (LGGs), the expression levels of YTHDF2, WTAP, ALKBH5, RBM15, KIAA1429, HNRNPC, YTHDF1 and FTO were significantly correlated with the overall survival (OS) of IDH-mutated glioma patients. This evidence concerns the gene YTHDF2 and central nervous system cancer.