IFNG and neoplasm: This may be because SBHFRT rather than CFRT can induce higher expression levels of T helper lymphocytes and cytotoxic T lymphocytes, especially 7 days after radiation; promote the accumulation of the anti-tumor cytokine IFN-γ [29]; regulate T lymphocyte decrease, which is beneficial to reduce tumor cell immunosuppression; and recruit more DCs and cytotoxic T lymphocytes, enhancing tumor cell antigen recognition, and in turn having a stronger antitumor effect [27, 29].