Table 2 indicated the characteristics of the overlap genes. Table 3 displays a summary of biological pathways related to the TAPBP, BDNF, and SORBS2. Table 4 shows pathway analysis interaction for overlapped genes in obesity and mood disorders. Figure 2 demonstrate gene interaction between overlapped genes in obesity and mood disorders by the genemania software. The gene discussed is TAPBP; the disease is obesity due to melanocortin 4 receptor deficiency.