Similarly, the proteins endothelial lipase precursor, apolipoprotein A-IV precursor, and carcinoembryonic antigen-related cell adhesion molecule 8 precursor were reported to be expressed uniquely in patients affected by Hodgkin’s disease, suggesting an impairment of metabolic processes and pathways related to the production and synthesis of reactive oxygen species (ROS) [23]. This evidence concerns the gene APOA4 and Hodgkins lymphoma.