CD4 and infection: To test whether autologous CD8+ T cells from HIV-uninfected healthy subjects suppress viral replication in infected CD4+ T cells, TCR-activated Red+CD8+ T cells were added after infection of Vio+CD4+ T cells with a replication-competent NL4-3_eGFP virus, and then co-cultured for 72 hours at 1:1 and 5:1 CD8 to CD4 ratios.