SCGB1A1 and pulmonary fibrosis: In contrast, the proportion of SCGB1A1+SCGB3A2high club cells was similar to the controls, but the transcriptome of the SCGB1A1+SCGB3A2high club cells was significantly dysregulated in IPF, with increased gene expression related to extracellular matrix formation, mucins and the growth factors relevant to pulmonary fibrosis.