The individuals had a poorly controlled type 2 diabetes (defined as HbA1c of > 7.5% and/or unstable glycemic control with recurrent hypoglycemia, mean HbA1c 8.39 ± 0.24%, 68.1 ± 2.6 mmol/mol), and a prothrombotic state (mean FXa generation 526.4 ± 38.2 U/mL). Here, F10 is linked to type 2 diabetes mellitus.