INS and cardiovascular disorder: In terms of changes in patient numbers, the number of patients undergoing insulin therapy increased by 21,649 people over 20 years, and the number with macroalbuminuria increased by 830 people over 20 years, whereas the number of patients with microalbuminuria decreased by 13,547 people over 20 years, with ESRD by 22 people over 20 years, undergoing dialysis by 23 people over 20 years, and with cardiovascular disease by 3357 people over 20 years.