EIF6 and Shwachman-Diamond syndrome: Loss of one copy of the human EIF6 gene is a recurrent finding in bone marrow cells of Shwachman–Diamond syndrome patients and is associated with a relatively benign clinical course (Pressato et al, 2012; Valli et al, 2019), suggesting that this bypass suppressor mechanism is conserved from yeast to humans (Weis et al, 2015; Tan et al, 2019), and supporting a rationale for the development of small‐molecule eIF6 suppressor mimics for the treatment of Shwachman–Diamond syndrome.