Significant differences were found between FAM161A patients as a group and patients with RP due to MAK (p < 0.001), RPGR (p < 0.001) and DHDDS mutations (p = 0.005), with FAM161A patients showing more severe constriction of visual fields at earlier ages (Supplementary Table S4). This evidence concerns the gene RPGR and retinitis pigmentosa 1.