Interestingly, ASNS mRNA levels correlate with DENR•MCTS1 levels in individual cancer entities such as liver hepatocellular carcinoma (r > 0.35), lung squamous cell carcinoma (r > 0.5) and renal cancer (r > 0.49, Supplementary Fig. 7g–i), and indeed throughout the entire TCGA pan-cancer set (r > 0.36, Fig. 5h). This evidence concerns the gene MCTS1 and squamous cell lung carcinoma.