Sequencing data revealed uniquely elevated markers attributable to the GBM core (CD44, MYC, HIF1α, VIM, ANXA1, CDK6, and JAG1) and the GBM edge (OLIG1, TC2, SRRM2, ERBB3, PHGDH, and RAP1GAP) (Fig. 1c). Here, RAP1GAP is linked to glioblastoma.