Sequencing data revealed uniquely elevated markers attributable to the GBM core (CD44, MYC, HIF1α, VIM, ANXA1, CDK6, and JAG1) and the GBM edge (OLIG1, TC2, SRRM2, ERBB3, PHGDH, and RAP1GAP) (Fig. 1c). This evidence concerns the gene HIF1A and glioblastoma.