By analyzing the PPI network, the 10 hub DEGs ITGAL, TLN1, POLR2A, CD69, GZMA, VASP, HNRNPUL1, SF1, SRRM2 and ITGAV were selected, among which ITGAL, TLN1, POLR2A, VASP, HNRNPUL1, SF1 and SRRM2 were expressed at higher levels while the expression levels of CD69, GZMA and ITGAV were lower in FH patients. Here, SF1 is linked to familial hyperaldosteronism.