In particular, it has been reported that non-toxic doses of 15d-PGJ2, DHA, and troglitazone reduce breast cancer cell invasion through the downregulation of the matrix metalloproteinases-9 (MMP9), a protease implicated in the extracellular matrix degradation in MCF-7 breast cancer cells [118,119,120]. Here, MMP9 is linked to breast carcinoma.