HDAC2 and hepatocellular carcinoma: HDAC2 and PPM1F were direct targets of miR-490-3P and miR-149-5p, and overexpression of SNHG15 and SNHG8 in HCC showed a correlation between HDAC2 and PPM1F expression via the absorption of miR-490-3P and miR-149-5p, respectively [65,66].