PRKN and Parkinson disease: In addition, genetic studies have revealed that many causal genes of monogenic Parkinson’s disease, such as Parkin (PARK2) [91], PINKl (PARK6) [92], DJ-1 (PARK7) [93], Omi/HtrA2 (PARK13) [94], and CHCHD2 (PARK22) [95,96], are associated with mitochondrial functions and quality control [77,97].