The two pathways were also scored as the most visited pathways in the fibroblasts “ataxia” and peripheral blood “ataxia” datasets, followed among others by TGF-beta signaling pathway, AMPK signaling pathway, mRNA surveillance pathway, neurotrophin signaling pathway, FoxO signaling pathway and insulin signaling pathway (Figure 3). The gene discussed is INS; the disease is cerebellar ataxia.