In this respect, MYL2 is linked to cardiac development and function [51], while MYL9 is involved in smooth muscle and non-muscle cell contractile activity e.g., in the gut and urinary tract [52], with ADNP syndrome children suffering cardiac as well as gastrointestinal problems [17]. The gene discussed is MYL2; the disease is ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder.