Next, to study the ILC and NK cell responses to HIV infection in pediatric tissue, we purified the dominant ILC (ILC3 NKp44–, ILC3 NKp44+) and NK cell subsets (NK CD127–) from pediatric tonsils, while insufficient cell numbers were available from ILC1 and ILC2 subsets (see Figure S3A), and performed transcriptional profiling directly ex vivo to characterize both the transcriptional differences between the subsets and their responses to HIV infection (Figure 6). Here, CCL27 is linked to HIV infectious disease.