Overall these results underline the importance of IFNL4 expression (IFNL4 rs12979860[T] variant) and low hepatic expression of PD‐1, found in the GCAT haplotype, in predicting HCV‐related HCC (OR = 2.101; 95% CI, 1.265‐3.491, Table 4). Here, PDCD1 is linked to hepatocellular carcinoma.