Indeed, the rs12979860[T] polymorphism necessary for IFNλ4 production is associated with HCC (Table 2) and the frequency of the genotype necessary for fully active IFNλ4 expression is higher in HCC (no G58R or P70S variant in 15 of 28, 54%) than in all other HCV‐positive patients (17 of 48, 35%) (Table 3). The gene discussed is IFNL4; the disease is hepatocellular carcinoma.