The IFNL4 rs12979860[T] allele associated with HCV positivity (n = 734) compared to BD (n = 98), in a log‐additive model with an odds ratio (OR) of 1.86 (95% CI, 1.33‐2.60, P < .0001), that remains significant after both Bonferroni's and Sidak's corrections. This evidence concerns the gene IFNL4 and Behcet disease.