Previous studies have reported that PPARα gene expression is correlated with disease severity and histological treatment response in patients with non‐alcoholic steatohepatitis (Francque et al., 2015), and several other studies showed that downregulated PPARα induces hepatic steatosis in animal models (Loyer et al., 2016; Lu et al., 2014; Montagner et al., 2016; Zhang et al., 2018), emphasizing its critical role in hepatic steatosis. This evidence concerns the gene PPARA and fatty liver disease.