Furthermore, two survival analyses on the TCGA (Cancer Genome Atlas Project) and METABRIC (Molecular Taxonomy of Breast Cancer International Consortium) data set showed that a worse survival probability was associated with the lower BECN1 but not with the BRCA1 mRNA expression in all breast cancer types,47 indicating that in sporadic breast cancers, BECN1 is a driver rather than a passenger event. Here, BRCA1 is linked to breast cancer.