Therefore, to confirm that the lack of response to HD treatment in SARS-CoV-2-infected patients was due to decreased MIR2911 absorption caused by the SIDT1 polymorphism, circulating exosomes from WT and polymorphic subjects before and after consumption of HD were isolated and incubated with cells expressing S-protein or SARS-CoV-2 virus (Fig. 1f). The gene discussed is PROS1; the disease is Huntington disease.