XPO1 and leukemia: In transfected cells, the application of LMB and KPT-185 similarly caused the dissolution of SET-NUP214-GFP and DEK-NUP214-GFP nuclear bodies and their homogenous distribution throughout the nucleoplasm, supporting the idea of an interplay between CRM1-mediated nuclear export and leukemia-related NUP214 fusion proteins (Supplementary Figure 2A).