Zhao et al (40), reported that co-administration of curcumin and paclitaxel exerted a good antitumor effect in multi-drug resistant ovarian cancer cells (SKOV3-TR30) and in ovarian tumor-bearing nude mice, since curcumin reversed the resistance to paclitaxel by inhibiting the drug efflux mediated by MDR-1 (40). This evidence concerns the gene ABCB1 and ovarian carcinoma.