Activation of the STING pathway not only causes cytokine release, but also induces apoptosis in immune cells, including in T and B lymphocytes [111], myeloid lineage cells, and in nonimmune cells, such as hepatocytes [112, 113] and cardiomyocytes [114], and in cancer cells [70, 110, 115]. This evidence concerns the gene STING1 and cancer.