Analogous with our clinical findings, during the progression of muscular dystrophy in the mdx mouse model, autophagy-related molecules (including Map1lc3b, Sqstm1/p62, and Becn1) were increased at the early stage (1.5 months) and progressively reduced at later stages (5, 8, and 12 months) in muscles, and this variation was closely related to the regenerative capacity of satellite cells52. This evidence concerns the gene BECN1 and muscular dystrophy.