VEGFA and myocardial infarction: According to Ai et al., intraperitoneal S. miltiorrhiza injection at doses of 3 or 6 g/kg per day for 4 weeks had beneficial effects on impaired cardiac angiogenesis in a rat model of myocardial infarction via up-regulation of expression of key proangiogenic factors, hypoxia-inducible factor 1α (HIF1α) and vascular endothelial growth factor A (VEGFA) [50].