MicroRNA-34a (miR-34a) represents a marker for steatosis, inflammation, and hepatocyte ballooning; alpha-2 macroglobulin and YKL40 represent markers for hepatic fibrosis, and YKL40 is also involved in inflammation and tissue remodeling in response to endothelial dysfunction. This evidence concerns the gene CHI3L1 and Hepatic fibrosis.