To study the cytotoxicity of iKP-19-CAR-T cells on CD19+HLA-C1− Burkitt’s lymphoma cells or CD19+HLA-C1+ normal B cells in vivo, Daudi cells expressing luciferase were generated and were injected intravenously (i.v.)into six-week-old NOD-Prkdcem26Cd52IL2rgem26Cd22/Nju (NCG) mice via tail veins on day 0 and normal B cells were injected in the same way on day 6 (Figure 6A). The gene discussed is CD19; the disease is Burkitt lymphoma.