FZD10 and colorectal carcinoma: The relevant involvement of the FZD10 in CRC was also proved by our in vitro study, which revealed the presence of FZD10 and FZD10-mRNA in exosomes extracted from culture medium of the metastatic CRC, gastric, hepatic and cholangial cancer cell lines, namely HGC-27, SW-620, N-87 and HUCCT-1 cells.