In this regard, we preliminarily evaluated whether significant correlations occurred between the combined gene expression of selenoproteins and HUB nodes (based on clustering in the matrix analysis shown in Figure 5B), and the OS of prostate cancer patients; this analysis was performed using the PROGgeneV2 online tool (http://genomics.jefferson.edu/proggene/index.php) [47]. Here, SELENOS is linked to Familial prostate cancer.