MYC and cancer: The HUB nodes include the well-known oncogene MYC, which is amplified in various types of cancer, such as breast, colorectal, endometrial, ovarian, and prostate cancer, and controls the expression of genes and noncoding RNAs by regulating cell growth, cell cycle progression, apoptosis, and differentiation, as well as angiogenic switch, cellular metabolism, and drug resistance mechanisms [31,32].