While Sumathi et al. [21] previously showed that diffuse WT-1 positivity is characteristic of endometrial stromal neoplasms and may be of value in diagnosis, we noticed that the WT1 gene is often absent or with low expression levels in HG tumors as compared to the others (Figure S4E), suggesting that WT-1 might be a prognosis factor in ESS. This evidence concerns the gene WT1 and endometrioid stromal sarcoma.