Signalling by interleukins (R-HSA-449147) associated with cluster 1 (annotated as LIF, LIFR, STAT3, IL15, JUNB, FOS, SOCS3, ANXA2, BCL6, IL6, IL10, CXCL2, CCL3 and CCL3L3) and interleukin-4 and interleukin-13 signalling (R-HSA-6785807) enriched by both adenomyosis and endometriosis gene lists (annotated as IL10, STAT3, LIF, SOCS3, IL6, VIM, FOS, JUNB, VEGFA and HSP90B1) were highlighted as source pathways for candidate genes selection. The gene discussed is FOS; the disease is endometriosis.