A more recent, second study from the Cornell-Weill Institute in New York [13] examined Day-2 IGF-1 serum levels in 184 women undergoing IVF and found those with levels >72 ng/mL (equivalent to 9.4 nmol/L) had a significantly higher risk of developing ovarian hyperstimulation syndrome. This evidence concerns the gene IGF1 and ovarian hyperstimulation syndrome.