Greig cephalopolysyndactyly syndrome (GCPS; OMIM number: 175700), Pallister-Hall syndrome (PHS; OMIM number: 146510), and postaxial polydactyly type A1 and type B3 (PAPA1 and PAPB; OMIM number: 174200) are resulted from heterozygous mutations of GLI3 [73,74,75]. Here, GLI3 is linked to Pallister-Hall syndrome.