Our recent studies demonstrated that some passenger strands of miRNAs, e.g., miR-143-5p, miR-145-3p and miR-150-3p, behave as tumor-suppressive miRNAs in LUAD cells by targeting oncogenes, e.g., LMNB2, MCM4 and TNS4, respectively [22,23,24]. The gene discussed is LMNB2; the disease is neoplasm.