Another study reported that more than 50% of PD-1 or PD-L1 expression was associated with enhanced response to PD-1 inhibition treatment in solid tumors, and a higher percentage of PD-1 and PD-L1 was found in circulating CD34+ cells in blood samples from MPN patients than in samples from healthy donors [126]. The gene discussed is CD274; the disease is myeloproliferative neoplasm.