CTNNB1 and hepatocellular carcinoma: Noncoding RNAs have also been shown to act as key cofactors of HuR to promote cell proliferation, as shown in the case of UFC1, a long-intergenic noncoding RNA overexpressed in human HCC, which enhances HuR stabilization of the CTNNB1 mRNA, thereby stimulating the proliferation of HCC cells [133].