Finally, based on gene set enrichment analysis, the high expression of HNRNPA1 in HBV-related HCC has been suggested to affect cell cycle progression and the WNT signaling pathway, pointing to HRNPA1 as a potent oncogene regulating the epidermal growth factor receptor (EGFR) signaling pathway [66]. This evidence concerns the gene EGFR and hepatocellular carcinoma.