Thanks to the advancement of next-generation sequencing technologies, we now have a clearer indication of which DNA repair-related genes are mutated in each specific cancer: for example, some breast and ovarian cancers are characterized by mutations in BRCA1/BRCA2, while alterations in MMR genes such as MSH2 or MLH1 are related to colorectal cancer [12]. This evidence concerns the gene BRCA1 and cancer.