LMNA and familial dilated cardiomyopathy: In addition, mutations in extra-desmosomal genes are reported, such as TTN, FLNC, LMNA, TMEM43, DES, PLN, genes typically associated with DCM, and SCN5A, more frequently associated with BrS or LQTS; nevertheless, molecular epidemiology studies showed a low frequency of mutations in these genes.