On the other hand, Karlsson et al. showed that EVs isolated from the murine PCa cell line TRAMP-C1 inhibited the development of the osteoclast lineage, decreasing the expression of established markers for osteoclast fusion and differentiation, including dendritic cell-specific transmembrane protein (DC-STAMP), TRAP, cathepsin K (CTSK), and matrix metallopeptidase (MMP)-9 [62]. The gene discussed is DCSTAMP; the disease is posterior cortical atrophy.