MMP14 and renal cell carcinoma: Meanwhile, we observed a negative correlation between miR-485-5p and MMP14 expression in RCC samples (Figure 4I) and western blot showed that the protein level of MMP14 was altered following transfection with miR-485-5p inhibitors or mimics (Figure 4J), which also demonstrated that MMP14 is targeted by miR-485-5p.