MTSS1 and pachyonychia congenita: Matrigel-coated Transwell and wound-healing assays showed that the invasion and migration abilities of BxPC-3/PANC-1 cells transfected with siMTSS1-AS significantly increased (Figure S2C-D), suggesting that MTSS1-AS was involved in regulating the migration and invasion abilities of PC cells in acidic environments.